What makes a cell a cell? And which drug to use for which patient? These are questions I'm addressing in my research by a combination of quantitative data generation and deterministic modelling.
To die or not to die needs to be decided by every cell individually. How signal transduction leads to cell-fate decisions, I study with single-cell resolution by interdisciplinary approaches.
We discovered a subset of phagocytic cells that protect the human body from systemic leakage of lipids and related metabolites, which is investigated with cutting-edge technologies.